ABSTRACT
Objective To investigate the effect of aspirin on platelet biochemical index in patients with cardio-cerebrovascular diseases and the influence of Naoxintong(Brain-heart unobstruction)Capsule.Methods The blood samples of 215 patients taking aspirin 100 mg per day for 7 days were collected for determination of platelet aggregation(PAG),P-selection level and TXB2 level by using arachidonic acid(AA)and adenosine diphosphate(ADP).Then they were divided randomly into aspirin group 1(n=72),still taking aspirin 100mg per day,aspirin group 2(n=70),taking aspirin 300mg per day,and Naoxintong group(n=73),taking aspirin 100mg per day and Naoxintong Capsule.One month later,their PAG,P-selection and TXB2 levels were re-examined.Results The plasma P-selection and TXB2 were in a positive correlation with AA-and ADP-induced PAG(P